The renin-angiotensin system in obesity

metabolic and hemodynamic effects

Abdominal obesity plays a central role in the metabolic syndrome and is a major risk factor for type 2 diabetes mellitus and cardiovascular disease. Unravelling the underlying mechanisms of obesity and obesity-related metabolic and hemodynamic disorders, such as insulin resistance and hypertension, may increase the rationale for dietary and/or pharmacological strategies to prevent or treat type 2 diabetes and cardiovascular disease.

Gijs Goossens, June 28th 2006